Institut für Systembiotechnologie


  • Hoffmann SL, Kohlstedt M, Jungmann L, Hutter M, Poblete-Castro I, Becker J, Wittmann C (2021)

    Cascaded valorization of brown seaweed to produce L-lysine and value-added products using Corynebacterium glutamicum streamlined by systems metabolic engineering.

    Metab. Eng. In press.

  • Millard P, Sokol S, Kohlstedt M, Wittmann C, Letisse F, Lippens G, Portais JC (2021)

    IsoSolve: an integrative framework to improve isotopic coverage and consolidate isotopic measurements by MS and/or NMR.

    Anal. Chem. In press. PREPRINT.

  • Gläser L, Kuhl M, Stegmüller J, Rückert C, Myronovskyi M, Kalinowski J, Luzhetskyy A, Wittmann C (2021)

    Superior production of heavy pamamycin derivatives using a bkdR deletion mutant of Streptomyces albus J1074/R2.

    Microb. Cell Fact. 20:111. PUBMED.

  • Tangyu M, Fritz M, Aragao-Börner R, Ye L, Bogicevic B, Bolten CJ, Wittmann C (2021)

    Genome-based selection and application of food-grade microbes for chickpea milk fermentation towards increased L-lysine content, elimination of indigestible sugars, and improved flavour.

    Microb. Cell Fact. 20:109. PUBMED.

  • Wolf S, Becker J, Tsuge Y, Kawaguchi H, Kondo A, Marienhagen J, Bott M, Wendisch VF, Wittmann C (2021)

    Advances in metabolic engineering of Corynebacterium glutamicum to produce high-value active ingredients for food, feed, human health, and well-being.

    Essays Biochem. EBC20200134. PUBMED.

  • Gummerlich N, Manderscheid N, Rebets Y, Myronovskyi M, Gläser L, Kuhl M, Wittmann C, Luzhetskyy A (2021)

    Engineering the precursor pool to modulate the production of pamamycins in the heterologous host S. albus J1074.

    Met. Eng. 67:11-18. PUBMED.

  • Kuhl M, Rückert C, Gläser L, Beganovic S, Luzhetskyy A, Kalinowski J, Wittmann C (2021)

    Microparticles enhance the formation of seven major classes of natural products in native and metabolically engineered actinobacteria through accelerated morphological development.

    Biotechnol. Bioeng. in press PUBMED

  • Jovanovic S, Dietrich DL, Kohlstedt M, Becker J, Wittmann C (2021)

    Microbial production of polyunsaturated fatty acids – high-value ingredients for aquafeed, superfoods, and pharmaceuticals.

    Curr. Opin. Biotechnol. 69:199-211. PUBMED.