Institut für Systembiotechnologie

Publikationen

  • Christmann J, Cao P, Kohlstedt M, Goldbeck O, Riedel CU, Becker J, Wittmann C (2026)

    High-copy plasmid engineering enhances recombinant protein and antimicrobial peptide production in Corynebacterium glutamicum.

    Microb. Cell Fact. In press.

  • Muhovic B, Bartolome MP, Enrico LLT, Dupont L, Jonas AM, Glinel K, del Campo A, Wittmann C (2026)

    Engineering Corynebacterium glutamicum as a multifunctional biofactory for living therapeutic materials and controlled ectoine delivery.

    Biomat. Adv. In press.

  • Mees DJ, Cao P, Ternes MV, Thönes A, Kohlstedt M, Wittmann C (2026)

    Substrate-informed metabolic engineering of Corynebacterium glutamicum enables balanced glucose–xylose co-utilization for the valorization of lignocellulosic feedstocks.

    Metab. Eng. 95:111-130.

  • Qi H, Ries F, Jovanovic-Gasovic S, Dietrich D, Gemperlein K, Müller R, Kohlstedt M, Wittmann C (2026)

    Acetyl- and malonyl-CoA availability drive EPA selectivity in polyketide synthase-engineered Yarrowia lipolytica.

    Microb. Cell Fact. In press.

  • Dietrich D, Qi H, Jovanovic-Gasovic S, Kohlstedt M, Wittmann C (2026)

    Defined YNB-free mineral medium improves reproducibility and enables high-titer production in Yarrowia lipolytica.

    Microb. Cell Fact. 25:59.

  • Sommer A, Pauli S, Kohlstedt M, Becker J, Wittmann C (2026)

    Metabolic engineering of Corynebacterium glutamicum for high-yield de novo biosynthesis of 5-aminovaleramide, a promising bio-based monomer.

    Microb. Cell Fact. 25:54.

  • Driller M, Grad M, Dielentheis-Frenken MRE, Stein K, Kohlstedt M, Wittmann C, Blank LM, Tiso T (2026)

    Aureobasidium pullulans NRRL 62042 as robust platform for efficient lignin valorization and sustainable cis,cis-muconic acid production.

    Biores. Technol. 443:133851. PUBMED.