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Latest Publications

  • Hoffmann, SL, Jungmann, L, Schiefelbein, S, Peyriga, L, Cahoreau, E, Portais, JC, Becker, J, Wittmann, C (2018)

    Lysine production from the sugar alcohol mannitol: Design of the cell factory Corynebacterium glutamicum SEA-3 through integrated analysis and engineering of metabolic pathway fluxes.

    Metab. Eng. In press. PUBMED.

  • Schwechheimer SK, Becker J, Peyriga, L, Portais, JC, Sauer, D, Müller, R, Hoff, B, Haefner, S, Schröder, H, Zelder, O, Wittmann, C (2018)

    Improved riboflavin production with Ashyba gossypii from vegetable oil based on 13C metabolic network analysis with combined labeling analysis by GC/MS, LC/MS, 1D, and 2D NMR

    Metab. Eng. In press. PUBMED.

  • Kohlstedt, M, Starck, S, Barton, N, Stolzenberger, J, Selzer, M, Mehlmann, K, Schneider, R, Pleissner, D, Rinkel, J, Dickschat, JS, Venus, J, van Duuren, J, Wittmann C (2018)

    From lignin to nylon: Cascaded chemical and biochemical conversion using metabolically engineered Pseudomonas putida.

    Metab. Eng. 47:279-293. PUBMED.

iSBio News

Metabolic engineering provides new opportunities to improve nutrition and global food security

Since the advent of modern biotechnology, we have experienced a tremendous development, driven and inspired by demand, competition, and the quest for novel, exclusive and sustainable products from renewable resources. Nature itself delivers a diversity of organisms, enzymes, pathways, and metabolic...


Fermentation of Cocoa Beans Requires Precise Collaboration Among Two Bacteria, and Yeast

WASHINGTON, DC – June 10, 2014 – Good chocolate is among the world’s most beloved foods, which is why scientists are seeking to improve the product, and enhance the world’s pleasure. A team of researchers from Germany and Switzerland—the heartland of fine...


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